Girl Zone is set in a distant future where two girls embark on an intergalactic adventure to combat boredom, one of the galaxy's worst enemies. Their mission takes them to various planets, where they hope to find excitement and stimulation to cure their boredom.
The gameplay features ten basic mini-games that cater to young girls' interests, such as dress-up, collecting animals, beach relaxation, and a side-scroller avoiding nasty creatures while collecting points. Completing all the mini-games unlocks an additional mystery 11th game, adding an extra layer of excitement to the experience.