NHL 06

The gameplay has seen significant changes, with deking now performed using the left analog stick. This allows players to execute swift signature moves that confuse opponents and reward skill. The same stick is used to increase accuracy when shooting, with a bull's-eye appearing in the enemy goal that can be quickly moved to the corners for precision. Additionally, statistics such as speed and size are reflected during gameplay in the players' momentum and turning radius.

New features include R.P.M. (Realistic Puck Momentum) dynamics, which adds more randomness with the puck, including the possibility of a shot off the mask stunning goalies. Another addition is the deformation of the ice during matches. In the player creation mode, players can now apply bruises, broken noses, black eyes, and scars to their players using the thumbstick for "face sculpting" – changing the different features.

All regular game modes are present, including Dynasty Mode, which has been improved with scouting and full management options, both inside and outside the arena. One notable change is that players can now intervene during simulated AI games and win the match for their team.