The gameplay is similar to Neo Contra with a behind-the-back view where the player uses a variety of weapons including machine guns and rocket launchers, along with the Delta 6 Accelerator Suit that makes the player invulnerable for a short period. The player must fight their way through hordes of enemies including soldiers, tanks, and jet fighters, as well as standard end-of-level bosses.
The player can choose from 12 different Joes, but only a certain set at the beginning, unlocking more by completing missions. Each Joe has their own weapon and strengths depending on their rank: Commandos are great at close range, Heavy Weapons are good at shooting from long distances while Soldiers are a mix of both. The game also features vehicles scattered throughout the stages and a two-player co-op option that allows a friend to join a game at any time.