Metro City, 2026. A corrupt mutant group called "Scumocide" plots to control the universe. The hero, Captain Commando , assembles a team of three renegades; Ginzu the Ninja, Baby Head, and Mack the Knife; to help him foil Scumocide's plans. This task will not be easy as many of Earth's institutions are infested with Scumocide's minions, but strength and persistence runs the team into the crusade.
The player chooses one of these four characters, who must fight their way through an army of genetically engineered super-criminal, traveling through a series of locations such as the bank, museum, circus, aquarium, and several others, right through to a planet called "Callisto", where the evil behind "Scumocide" awaits. Each character has their own special attacks. Captain Commando can use the power of his suit to shoot electricity through his palms. Baby Head rides around in a mech suit which does more damage. Mack can use short knives. Each location ends with the character defeating a boss before proceeding to the next one.
The gameplay is fast-paced and action-packed, requiring the player to master each character's unique abilities to overcome the challenges ahead.