The marines can draw on a variety of guns, most of them featured prominently in the movie. The motion tracker radar displays both human survivors as well as hostile aliens, but requires a free hand to use. Another item from the movie is the power loader, which slows down the marine but increases their health at the same time.
The enemies include the entirety of the alien life cycle, from facehuggers to chestbursters, adult alien warriors, and a queen. As the game progresses, they gain the ability to spit acid. Lost health can be regained by collecting and using first aid kits. Game progress is saved through the use of passwords.