In this post-apocalyptic driving/racing game you must travel to various towns delivering medicine, while on your way to a missile base which houses a rocket that can save the world. Your goal is to navigate through 32 levels, avoiding enemies who want to stop you from achieving it.
Fatal Run features many weapons at your disposal, including dynamite, rockets, oil slicks, smoke screens, and machine guns. You can also upgrade your vehicle within the city shops. Upgrading your gas tank provides better mileage while upgrading your bumper protects you during collisions. A password feature lets you continue where you left off.