NBA 2K11 features a narrative that revolves around Michael Jordan's career in basketball. The game includes four modes centered around Jordan's achievements, such as the "Jordan Challenge" where players recreate his performances from various games throughout his career.
The gameplay involves advanced controls like revised "Iso-Motion" dribbling and "Shot Stick" controls for better shot control, as well as an "On-The-Fly Coaching" system that allows players to change AI strategies or call out new ones in multiplayer. The game also features a "Shot Branching" system allowing players to adjust shots while airborne.
Players can engage in various modes such as "My Player," where they create a rookie player and guide him through an NBA career, including on-court gameplay and off-court interactions like press conferences and endorsements. In "Association" mode, players manage teams as both coach and GM, controlling scouting, player assignments, and salaries.
Online multiplayer allows for club formation, leagues, and the return of the "NBA Blacktop" mode with new additions like the "Slam Dunk Showdown." The game also features a "NBA Today 2.0" system that updates player stats and injuries in real-time, along with live news and improved presentation.