Following genetic experiments conducted by a group of scientists at the turn of the millennium, a biological explosion contaminated the genetic structure of life on Earth. Two attributes emerged from the ruins, known as Silhouette and Mirage; like Yin and Yang, they cannot exist without each other, but are fundamentally opposed in their nature and ideology. Only a Messenger, one who contains both attributes in a balance, is able to get to the Edo facility and reverse back the genetic disaster, destroying both Silhouette and Mirage. This messenger is a young girl named Shyna Nera Shyna.
Rage is an action-adventure game for the Playstation 3 console. The gameplay involves side-scrolling action, with Shyna able to dash, jump, crouch, slide, and grab enemies, executing combo attacks. As players progress through the levels, they can master new moves, acquire money, and purchase special creatures called "parasites", which teach Shyna various types of attacks. The game's unique attribute system allows for a variety of strategies, making each enemy encounter different and challenging.