The gameplay is similar to the original games, but now in 3D. Many sequences use the classic side view, but there are also many other perspectives used. Each turtle has a specific attack and the four turtles are always on the screen. When playing solo, the other turtles are controlled by the AI. During the game, the turtles have to be upgraded. This can be done by collecting points by defeating enemies and breaking items. Health of any of the turtles is increased by eating pizza's, sushi and other food items. The collectibles in this game are Mutagen Canisters which are used to unlock extras.