NFL Street 2 is the second game in EA's arcade football series. Players try to become the world's best urban footballer by conquering other teams using several gravity-defying tricks like up-the-wall passes, off-the-wall catches, and highlight-reel wall jukes. The gameplay focuses on arcade-style action with a small number of players, focusing on tricks and skills rather than traditional football tactics. Players can use the walls to their advantage, performing run-up passes and receptions, or scoring bonuses by aiming for posters and hotspots.
Single-player modes include NFL Street 2 's NFL Challenge, where players have 150 days to build a team and take on a squad of legends. The player's progress is based on milestones, sharpening specific skills to reach the top or beat sufficient teams. As the final tournament approaches, the team enters a high-pressure situation.
Another single-player mode is Own the City, where players create a new character and must win all street games in the city. New players need to be recruited from pick-up games, with the ultimate goal of beating a team featuring rapper Xzibit and a team of NFL stars. The PSP version of NFL Street 2 is a faithful port with some cutscenes removed, adding three new street modes for Wi-Fi multiplayer: Street Slalom, Style Point Challenge, and Style Standoff. These modes offer unique gameplay experiences, including an obstacle course and end zone dance contest.
Multiplayer options are available on the Xbox version, allowing up to four players to compete in various game modes, such as the 2 Minute Challenge and Jump Ball Challenge.