Fifteen years after the events of Ridley Scott's Alien, Amanda Ripley, Ellen Ripley's daughter, is searching for answers. She's an engineer working for Weiland-Yutani Corporation and discovers that the logs from USCSS Nostromo have been located and transported to Sevastopol space station. She decides to join a small crew sent by Weiland-Yutani to retrieve the data. Unbeknownst to her, the ship that found the logs reached Sevastopol with a terrifying passenger on board, one that murdered the majority of the station's population and left the survivors in fear.
Alien: Isolation is a survival horror game set on the Sevastopol space station where Amanda is searching for USCSS Nostromo logs. The station is divided into many areas, giving the player some freedom to explore. Areas may have multiple routes, hidden rooms, and ventilation shafts, while Amanda can backtrack through the station as needed. As the game progresses, Amanda's tools will be upgraded, allowing her to access previously out-of-reach areas.
Amanda is an engineer, so she can loot containers and bodies for resources and craft devices like noisemakers, smoke bombs, or Molotov cocktails to distract the enemy. Later, she acquires a flashlight, motion detector, and various weapons to defend herself against humanoid enemies – groups of hostile survivors or androids. However, Amanda is not a fighter, and each encounter should be carefully planned. Many actions take time, such as using a medpack, which requires her to stand perfectly still.
When Amanda draws attention from the alien, stealth is the only way to survive. The alien cannot be harmed, and it will kill Amanda in a single hit. In most cases, it doesn't follow a predetermined scripted route but relies on its senses to track Amanda down.
In addition to the main story mode, there's Survivor mode, where the player must escape from a specially designed map while fulfilling secondary objectives along the way, being aggressively hunted by the alien. This mode includes online leaderboards.